After that, after one day, the mice were displayed on the same image and treated with electric shock until they learned to connect the image to the pain. Finally, the team tested whether the mice will freeze in fear of in response to the sound. The “unrestricted” group did not. The mice were in the “associated” group-it was found that the complex emotional models that resemble the human being were also present in the mice.
Once Johansen and GU confirmed that the capacity was present, they were busy knowing how it was working.
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“From a behavioral point of view, we measured the frozen responses of the associated incentive, which was the image, and the incentive that was the sound.” “But we also had something that we called Miniscope Calcium.” The trick relied on the injection of mice with a virus that forced its cells to produce proteins that sparkle in response to the increase in calcium levels in the cells. Increased calcium levels is the sign of activity in nerve cells, which means that the team can see in real time, i.e. neurons in the brains of mice lit during experiments.
It turned out that the area necessary to build these complex emotional models was not the weight, but the dorsal frontal lobe (DMPFC), which had a somewhat specialized role. “DMPFC does not constitute the world’s sensory model. It is only concerned with things when it is of emotional importance,” explains. He said that there was no major change in neurological activity during the sensory learning stage, when the animals were watching the picture and listening to the sound. Nerve cells have become more active when mice received electric shock.
In the “unrestricted” group, the active neurons that held the representation of the electric shock began and the image began to overlap. In the “associated” group, this overlap also included the nervous representation of the sound. “There was a kind of bonding package that was formed,” says Johansson.
